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Senescent microglia may have a reduced capacity to modulate neuronal activity because of genetic changes that result in reduced surveillance, migration, and sensitivity to endogenous ligands, and a heightened sensitivity to pathogens, as seen in 24-month-old mice (Hickman et al., 2013
Reduces tumor formation in animal models
Skulachev for discussion of problems regarded in this paper
Bioengineering 11, 281
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