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(172) demonstrated that intravenous infusion of porcine GIP abolished plasma hypertriglyceridemia in rats during the fat load, while rats pretreated with GIP antiserum exhibited a significantly greater triglyceride increment late in the fat load time course

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For example, 70 mg efruxifermin dosed weekly, corresponding to two pharmacokinetic half-lives, appeared to improve HOMA-IR, fasting glucose, and fasting insulin in type 2 diabetes patients (246)

Effects of endogenous GIP in patients with type 2 diabetes

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