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WARNINGS Patients with early Lebers disease (hereditary optic nerve atrophy) who were treated with cyanocobalamin suffered severe and swift optic atrophy

once the compound clears, NNMT resumes normal activity

Weight loss as monotherapy is minimal, averaging 2-4 additional pounds monthly versus placebo in controlled settings

adults over 60 have a true B12 deficiency, and roughly 20% have marginal B12 status, according to research published in the American Journal of Clinical Nutrition