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M.BloomerW
In the presence of differentiation stimuli, abnormal protein folding in the ER activates the unfolded protein response (UPR) signaling, which can be alleviated by global translational attenuation, induction of molecular chaperones, misfolded protein degradation by endoplasmic reticulum-associated degradation (ERAD), and apoptosis (63)
In vitro work by Sikiric and collaborators shows BPC-157 upregulates VEGFR2 expression in endothelial cells, which stimulates angiogenesis, the growth of new blood vessels into healing tissue
Collagen synthesis Some animal studies claim that BPC-157 promotes the healing of skin tissue
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