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2023;37(7):e22960
The evidence base is overwhelmingly preclinical, and there are no completed, published Phase 2 or 3 human efficacy trials only early-stage safety work [9]
A proposal
Research shows the compound gives best results for studies that require frequent dosing or sensitive subject populations
Current evidence has pointed to shared microbiota changes in GD and depression, indicating that gut microbiome dysbiosis in GD may act as a trigger for depression (26, 150154)
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