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For Nerve Damage B12 can be injected under the skin to help heal areas affected by nerve damage caused by illnesses such as shingles

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doi:10.1076/opep.10.4.215.15906

While very high oral doses (1,000 to 2,000 mcg) can achieve some passive absorption without intrinsic factor roughly 1% of the dose is absorbed passively many clinicians prefer the reliability and rapid correction offered by injections in this population