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moreover, it increases the expression of vascular endothelial growth factor, which is a potent angiogenic factor, whereas tumor necrosis factor-, interleukin-6, and nuclear factor kappa B expression are inhibited, which benefits the healing of diabetic wounds (Qiang et al., 2017
doi: 10.7150/ijbs.83348 93 HuYHuangYZongLLinJLiuXNingS
Long-term metformin use and vitamin B12 deficiency in the Diabetes Prevention Program Outcomes Study
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