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Their clinical impact has since expanded dramatically due to their ability to induce sustained weight loss, improve insulin sensitivity, reduce systemic inflammation, and alter gut physiology

it should be borne in mind however that 5-oxoprolinuria may have other causes (see 'Differential diagnosis')

2 Saxenda (liraglutide), Wegovy (semaglutide)

9 The GSH redox cycle (the balance between GSH and GSSG) has been shown to be more effective than catalase in hydrogen peroxide detoxification in endothelial cell cultures

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