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Tirzepatide's amino acid sequence is derived from GLP-1, GIP, semaglutide, and a few unique residues

PMID: 20524875 [LoE A] [2] Weschawalit, S., Thongthip, S., Phutrakool, P., & Asawanonda, P

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Various structural alterations were made at the N-terminal such as substitution of D-norleucine for L-norleucine, N-acetylation of norleucine, and replacement of norleucine with GABA in order to improve overall stability by reducing susceptibility to aminopeptidases

Zdrowy organizm utrzymuje wysoki stosunek GSH do GSSG