For treating a deficiency, injections are usually given frequently at the start, for example, several times per week or every other day for a couple of weeks, to quickly build up body stores
It uses a methyl group donated by S-adenosylmethionine (SAM) to methylate nicotinamide a vitamin B3 form that would otherwise be recycled back into NAD+
In France, treatment involves the administration of 1,000 g (1 mg) of cyanocobalamin per day for 1 week, followed by 1,000 g (1 mg) per week for 1 month, followed by 1,000 g (1 mg) per month, again, normally for the remainder of the patients lifetime [10]
Penetrating muscle tissue is painful, and you might also hit a nerve by accident
MIC B12 injections work best when combined with these efforts