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In the case of eWAT, an increase in endogenous fatty acids following adherence to a HFD activates two sensors within adipocytes, Toll-like receptor 4(TLR4) and inflammasomes, which causes an influx of neutrophils to enter the eWAT, leading to increased levels of chemokine and cytokine expression (132)
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The results established that low dose sodium selenite supplementation led to a significant increase in GPx activity and the corresponding mRNA levels of GPx isozymes such as GPx1 , GPx2 , and GPx4 in the radiosensitive organs (spleen and intestine of mice)
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