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The S-acetyl modification serves two purposes: it makes the molecule more stable and resistant to degradation in the GI tract, and it may help the molecule cross cell membranes more easily than unmodified reduced glutathione

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Therefore, in the periphery, extracellular GSH reflects the antioxidant capacity of the liver, and the liver, due to its function in metabolizing xenobiotics and endogenous molecules, has high antioxidant capacity [16]

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