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Acknowledgements We thank all researchers and colleagues from Key Laboratory of Molecular Biology in Beijing Anding Hospital of Capital Medical University and Beijing Institute for Brain Disorders for their great support Ethics declarations Competing interests The authors declare that they have no conflict of interest

Introduction The term oxidative stress (OS) applies when increased amounts of reactive oxygen species (ROS) surpass the antioxidant (AOX) capacity that naturally offers the protective balance ( Hence, AOX therapy to enhance fertility by protecting against the harmful effects of ROS is theoretically feasible

These "essential" fatty influence various central nervous and immune system biochemical processes