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Human studies mainly used short-term intravenous DSIP injections under controlled research conditions, typically at 25 nmol/kg, but these studies were small, short-duration, and not designed to establish long-term safety or optimal dosing

Gray market peptides have been found to contain toxic heavy metals (like arsenic and lead)

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c-MET can either act as an immunosuppressive agent by negatively affecting dendritic cells (DC) and T lymphocytes or can stimulate immune response by promoting recruitment of DC, B-cells and T-lymphocytes [70]

This distinct mechanism amplifies the apoptotic cascade, even when protective proteins like Bcl-xL are present (175, 176)