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Animal studies have confirmed that various oxidative stresses can induce the release of highly acetylated HMGB1 under various pathological conditions The translocation of Cathepsin B from the lysosome to the nucleus induces DNA damage, leading to the subsequent release of HMGB1, which can induce the occurrence of ferroptosis[136]

Prior work established SLC25A39 as an mtGSH importer and identified a GSH-sensing stability loop that regulates SLC25A39 protein abundance

Sung J et al

Step 3 Protein Care - This step provides deep reconstruction and restoration of the hairs

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