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It serves as an excellent substrate for testing extracellular matrix (ECM) remodelling, angiogenic upregulation, and the modulation of cellular inflammatory pathways under induced stress

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Pinch the skin to create a fold, insert the needle at a 90-degree angle, and inject slowly

Percentages of proliferative (BrdU + ) (n = 6 technical replicates representative of 2 independent experiments) ( a ) and apoptotic (Annexin V + ) (n = 3 technical replicates representative of 3 independent experiments, **p = 0.0042) ( b ) cells were determined

Lobo RA, Gompel A