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Sources Novo Nordisk Wegovy HD (semaglutide 7.2 mg) FDA approval announcement, March 2026 The Lancet Diabetes & Endocrinology STEP UP trial: once-weekly semaglutide 7.2 mg in adults with obesity (2025) FDA Wegovy (semaglutide) prescribing information, 2025 PR Newswire FDA approves Wegovy HD injection (Novo Nordisk press release) NovoCare Wegovy cost and coverage information ClinicalTrials.gov STEP UP trial protocol (NCT05646706) New England Journal of Medicine STEP 1 trial: once-weekly semaglutide 2.4 mg Medical disclaimer This article is for informational purposes only and does not replace medical advice

It is a GLP-1/GIP/glucagon triple agonist a novel class distinct from dual agonists such as tirzepatide or single GLP-1 receptor agonists such as semaglutide

Novo Nordisk markets it as Ozempic (type 2 diabetes) and Wegovy (obesity)

Ensure that they understand the importance of ongoing monitoring, especially if they have any anatomical risk factors.

Increased Satiety and Reduced Appetite: One of the primary mechanisms through which Semaglutide aids weight loss is by regulating appetite