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Patients should never start, stop, or combine these medications without explicit guidance from their prescribing clinician
Eli Lilly has announced that Phase 3 clinical trials (the TRIUMPH programme ) are underway, investigating retatrutide across a broader population and over longer timeframes
doi:10.2337/dc13-2761
This can lead to weight loss over time as patients are consuming fewer calories per day
The REDEFINE Phase 3 program directly addressed this, showing CagriSema achieved 20.4% weight loss versus lesser results with semaglutide alone, cagrilintide alone, and placebo
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