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Renal Function Assessment Kidney function naturally declines with age, and renal considerations vary by agent

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GLP 1 stands for glucagon-like peptide-1, a hormone that helps control appetite, digestion, insulin production, and blood sugar

Tirzepatide 5 mg was associated with numerically lower odds and tirzepatide 10 and 15 mg were associated with numerically higher odds of experiencing nausea AEs compared with liraglutide, and all tirzepatide doses were associated with numerically higher odds of experiencing severe gastrointestinal AEs compared with liraglutide

Contrave side effects are most common during the first four weeks, which is also the dose-escalation period