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The odds of having each NASH histological component were significantly lower at the end of trial for patients who received semaglutide compared to placebo (e.g., in STEP 2 study for semaglutide 1.0 mg/week: 0.25 for steatosis and 0.52 for inflammation)

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General Eligibility Criteria: To qualify for many GLP-1 weight loss trials, participants are often adults between the ages of 18 and 65 (or as specified by the trial)

The available evidence suggests that oral glutathione and NAC supplementation are safe for long-term use at standard doses