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Authors' contributions: JS and DF participated in the conception and design of the review, revised the whole manuscript, and read and approved the final manuscript

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Research supports spreading protein intake across three to four meals or feeding events, with each meal containing a sufficient dose (typically 2540 grams of high-quality protein) to maximally stimulate MPS. GLP-1 users face a practical problem: appetite suppression often compresses eating windows and reduces meal size, making it difficult to hit adequate per-meal protein doses even when overall daily targets are attempted