Indicators used to determine the signalling profile of peptides include cAMP and intracellular Ca 2+ mobilisation, which are involved in promotion of insulin release, and pERK1/2 that is part of the mitogenic signalling pathways activated via the GLP-1R 12
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The underlying mechanism of these beneficial effects has been further investigated by Ohyama et al
Here enters the Gila monster, the largest lizard in North America
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