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Mistake #2: Going Too Low on Calories The problem: With appetite suppression, some people eat only 800-1,000 calories daily, thinking "if less is good, even less is better." Why it matters: Extreme calorie restriction triggers metabolic adaptation, increases muscle loss, causes fatigue, and makes weight regain more likely when you stop the medication

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However, TRP2 not only facilitates these biochemical conversions but also provides protection against oxidative stress by elevating intracellular glutathione (GSH) levels and mitigating the deleterious effects of quinones, thereby averting DNA damage initiated by free radicals