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Scorpion venom peptides with no disulfide bridges: a review
doi: 10.3389/fmicb.2024.1446595 Received 10 June 2024 Accepted 02 August 2024 Published 14 August 2024 Volume 15 - 2024 Edited by Daniela De Biase, Sapienza University of Rome, Italy Reviewed by Wolfgang Buckel, University of Marburg, Germany Malte Sinn, University of Konstanz, Germany Updates Copyright 2024 Piskol, Lukat, Kaufhold, Heger, Blankenfeldt, Jahn and Moser
Key Actions of KPV Downregulates pro-inflammatory cytokines Reduces NF-B signaling Promotes immune tolerance and balance Supports gut lining integrity Calms epithelial inflammation KPV is especially valuable in conditions involving chronic inflammation , whether localized (such as skin or joint inflammation) or systemic (such as gut-driven immune activation)
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These results appear clear-cut
