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This represents a physiological stress response rather than a direct drug effect
Time-to-onset analysis Time-to-onset was calculated as the duration between GLP-1 RA initiation and the occurrence of a NAE 21
Although tirzepatide is not likely to pass into breastmilk, there is limited human data on tirzepatide use while breastfeeding, which makes it difficult to fully assess infant safety
Bruising or Bleeding: Injecting into areas with visible veins or insufficient fat can increase the likelihood of puncturing a blood vessel, leading to bruising or minor bleeding
Second, by lowering insulin levels, these drugs may indirectly reduce androgen production by the ovaries
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