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The antioxidant response signals induce the activation of nuclear factor erythroid-derived 2-like-2 (Nrf2)

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An inverse association between cognitive decline and the ratio of w-3 to w-6 fatty acids in erythrocytes has been reported as well.10 Furthermore, increased fish and DHA intake were also found to be protective against cognitive decline and the risk of developing Alzheimer disease.11-14 Similarly, in our study, a 50% reduction in the risk of Alzheimer disease was associated with the consumption of more than 2 servings of fish per week