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Todays approval represents a significant step forward in enabling children to be treated with Brineura as early as possible, when we can have the greatest impact in altering the natural course of disease, Hank Fuchs, president of worldwide research and development at BioMarin, said in a statement
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It does not act on the hypothalamic-pituitary-gonadal (HPG) axis, which regulates testosterone secretion in the body
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P reduces the expression of P synthases, which leads to the decline of P level via the two mechanisms above (61, 62)
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