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Future therapeutic approaches may involve: Microbiome-targeted therapies Gut-derived peptide treatments Personalized nutrition based on microbial composition These emerging strategies reflect a broader shift in metabolic medicine toward addressing root causes rather than simply managing symptoms

The induction process transpires via interactions with pattern recognition receptors (PRRs), including Toll-like receptors (TLRs) and nucleotide-binding oligomerization domain-like receptors (NLRs), which are expressed on both intestinal epithelial cells and immune cells, including dendritic cells (108, 109)

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