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Long-term gastrointestinal outcomes in patients on teduglutide: a propensity-matched analysis
Eur J Clin Pharmacol 75 , 10371046 (2019)
Operational risks can be: Incomplete release of the tape Wound infections Scarring Injury to nerves or blood vessels During the healing process after the operation, the ligament tissue gradually grows back together and leaves more space for the nerve
Second-generation oral semaglutide, whose bioavailability and safety have been significantly improved by the application of new excipients and formulation optimization, but its gastrointestinal side effects are still obvious (Nielsen et al., 2025)
Together, these aspects warrant caution in the chronic use of GLP-1 receptor agonists during periods of active growth and maturation, reinforcing the need for long-term, sex-stratified studies to ensure safe and effective therapeutic application
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