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Major cardiovascular events, heart failure, and atrial fibrillation in patients treated with glucagon-like peptide-1 receptor agonists: an updated meta-analysis of randomized controlled trials
Judge Marstons August 15, 2025 ruling clarified: Clinical diagnosis based solely on symptoms is not sufficient You must have objective diagnostic testing Specifically: gastric emptying scan (4-hour scintigraphy study) Alternative tests: gastric emptying breath test or wireless motility capsule (SmartPill, though discontinued) Why this matters: Many patients were told they had gastroparesis based only on symptoms Without objective testing, defendants will challenge the diagnosis Court ruled that symptom-based diagnosis isnt reliable enough Need scientific proof of delayed gastric emptying What if you have symptoms but no formal testing
The participants taking collagen supplements had a higher increase in fat-free body mass and a decrease in fat mass
In the meantime, "policymakers and clinicians should continue to closely monitor trade-offs between pharmacologic and surgical management of obesity to ensure optimal access to effective obesity treatment," Tsai's group said
Slower Titration Often Makes Sense GI side effects like nausea, vomiting, and diarrhea are the most common reason patients reduce their dose or discontinue GLP-1 therapy
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