Practical recommendations include: Always take omega-3 supplements during or immediately after a meal Choose meals containing fat for optimal absorption If gastrointestinal symptoms persist despite taking with food, consider switching to enteric-coated or emulsified formulations If you have a fish or shellfish allergy, avoid fish-derived oils and consider algae-derived omega-3 alternatives During pregnancy, avoid cod liver oil supplements due to their high vitamin A (retinol) content [11] Consult your GP or pharmacist if you experience persistent digestive discomfort, as this may indicate intolerance or the need for an alternative preparation Morning vs Evening: When to Take Your Omega-3 Supplement The choice between morning and evening dosing of omega-3 supplements largely depends on individual lifestyle factors, meal patterns, and personal tolerance rather than significant pharmacological differences
251 Impaired neurotrophic support In DPN, levels of neurotrophic factors are significantly reduced due to hyperglycemia-induced metabolic disturbances
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