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STEP-1 lasted 68 weeks, SURMOUNT-1 lasted 72 weeks, and TRIUMPH-4 lasted 68 weeks, but the latter was conducted on a specific population (obesity with knee osteoarthritis)
At standard doses, a small air bubble is irrelevant
However, AMPK activity in the LH was still low, and exendin-4 treatment decreased AMPK activity in the VMH, whereas no significant effect was detected in the LH (Figure 5)
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