d-Allulose reduces feeding via GLP-1R in HFD-fed mice We next examined the effects of d-allulose on food intake in obese and diabetic mice
Bone health during chronic use: Long-term caloric restriction, regardless of mechanism, can affect bone mineral density
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doi:10.1136/bmjopen-2012-001986., Edwards CM, Todd JF, Ghatei MA, Bloom SR: Subcutaneous glucagon-like peptide-1 (7-36) amide is insulinotropic and can cause hypoglycaemia in fasted healthy subjects
This progress in scientific development enables a 1-week administration of the drug, making them an efficient alternative to other antidiabetic drugs, such as metformin, which requires two daily doses, and the updated metformin, which requires daily doses [100, 101]