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The field shows growing interest in novel delivery systems, including liposomal formulations, sublingual preparations, and buccal absorption methods, attempting to overcome the documented challenges of glutathiones poor gastrointestinal bioavailability

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Difficulty with Hydration: Trouble drinking enough fluids due to feelings of fullness or nausea

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A slower gastrointestinal system may lead to nausea when sedatives are administered, potentially increasing discomfort during the procedure