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The role of these chemicals is not fully understood, and more research is needed to validate the benefits of this chemical

Risks and Unknowns Remaining research gaps include: Long-term systemic administration data Optimal dosing strategies outside dermatology Interaction with copper metabolism disorders Comparative efficacy versus standard wound treatments Most evidence supports local, tissue specific effects rather than systemic transformation

Metformin carries a boxed warning for lactic acidosis and should not be taken by people with severe renal impairment or acute or chronic metabolic acidosis

Mojsov et al., 1987)

This is the starting dose regardless of what semaglutide dose you were on even if you were at 2mg Ozempic or 2.4mg Wegovy