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Evidence quality varies a lot depending on which BPC-157 claim you are looking at, and treating all of it as equally solid is a mistake

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Four-Octyl Itaconate Protects Chondrocytes against H(2)O(2)-Induced Oxidative Injury and Attenuates Osteoarthritis Progression by Activating Nrf2 Signaling

After 4 weeks of D-galactose injections, the D-Gal group mice received intraperitoneal injections of PBS every 2 days for 4 weeks, followed by tissue collection

2014 paper demonstrating Dihexa's synaptogenic effects through the HGF/c-Met system was retracted in April 2025 (PMID: 40312093)