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The search details are shown in Supplementary Table 1, meantime the inclusion criteria were as follows: (i) patients with PCOS, (ii) patients with the treatment of carnitine supplementation, (iii) patients with body weight information, (iv) patients with exact doses and durations of carnitine supplementation, and (v) patients with the control group

Signal detection was performed using a mouse- and rabbit-specific horseradish peroxidase (HRP)/3,3-diaminobenzidine (DAB) immunohistochemistry kit (#ab64264, Abcam, Cambridge, UK) according to the manufacturers instructions

Needles longer than 8mm increase the risk of reaching muscle, especially in leaner individuals and at injection sites with thinner subcutaneous fat

It does this by increasing the production of glutathione and other important neurotransmitters that are essential for healthy brain function