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Final products leave through the kidneys into urine or through bile into the intestine
ChughRMMittalPMpNAroraTBhattacharyaTChopraHet al
Compound MOTS-c Lyophilized 12+ months at -20 C Reconstituted (2-8 C) Up to 7 days Notes Limiting factor for the stack
Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent
Lactoferrin is a natural inhibitor of plasminogen activation
