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To deepen our understanding of these findings, we analyzed metabolomic data from the Cancer Cell Line Encyclopedia (CCLE) (DepMap) and confirmed that long-chain PUFAs were significantly enriched in BRAFi-resistant cells (Appendix Fig
Since an IgG1 antibody carries approximately 90 surface Lys residues (with ~30 available for conjugation), this method can yield heterogeneous species with 1 to 30 payloads
The nickname "Wolverine Stack" comes from the rapid tissue repair users report across tendon, muscle, ligament, and joint injuries
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