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Int J Pharm Sci Rev Res (2013) 23(1):8790
A: Degradation can sometimes be detected by changes in the appearance of the peptide solution (e.g., cloudiness, precipitation) or a loss of expected biological activity
Research on sublingual drug delivery shows this route can avoid first-pass liver metabolism and utilize the rich vascular network of the oral mucosa for direct absorption into the bloodstream
For a recombinant protein, a functional assay is not an optional extra on top of the chemistry
Efficacy of BAFF inhibition and B-cell depletion in non-obese diabetic mice as a spontaneous model for Sjgrens disease
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