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The modified version (CJC-1295 with DAC) has an extended half-life, providing sustained GH elevation throughout the day

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However, since this review, a subsequent study (KEEPS study) found that BMI increased significantly less (by 1.09kg/m 2 ) in women on HRT rather than placebo (241, 242)

The focus of most emerging therapeutic strategies currently is on developing glycolysis and lactate inhibitors, with few interventions directly targeting Kla pathways, leaving significant room for exploration

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