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Alongside GLP-1 is GIP (glucose-dependent insulinotropic peptide), made by K-cells higher up the intestine
Use of Liraglutide (Victoza, Saxenda) & Semaglutide (Ozempic, Wegovy, Rybelsus) Comes with Risk of Gastrointestinal Disorders Use of Liraglutide (Victoza, Saxenda) & Semaglutide (Ozempic, Wegovy, Rybelsus) Tied to Increased Risk for Pancreatitis and Bowel Obstruction A new study showed that use of the GLP1 agonist medications approved for diabetes and weight loss including liraglutide (Victoza, Saxenda) & semaglutide (Ozempic, Wegovy, Rybelsus) come with a 9X increased risk of pancreatitis, 4X increased risk of bowel obstruction and 3.5X increased risk of gastroparesis compared to controls
PLoS ONE 8 , e61166 (2013)
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Treatment is typically lifelong for patients with pernicious anaemia or irreversible malabsorption conditions
