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10.1007/s40265-023-01932-2 66

Because there are always downsides

Delayed gastric emptying can increase intragastric pressure and potentially promote gastroesophageal reflux, particularly in patients with pre-existing GERD or those who overeat despite reduced appetite signals

Differential effects of intra-ventral tegmental area ghrelin and glucagon-like peptide-1 on the stimulatory action of D-amphetamine and cocaine-induced ethanol intake in male Sprague Dawley rats

Approximate equivalency chart These are rough guidelines based on clinical observation, not precise conversions: Semaglutide 0.25-0.5mg corresponds roughly to tirzepatide 2.5-5mg Semaglutide 1mg corresponds roughly to tirzepatide 5-7.5mg Semaglutide 1.7mg corresponds roughly to tirzepatide 7.5-10mg Semaglutide 2.4mg corresponds roughly to tirzepatide 10-15mg These equivalencies suggest where you might eventually land, not where you should start