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Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al

The anti-obesity drug semaglutide may lower the risk of death from COVID-19, cardiovascular disease, and all causes, according to a randomized controlled trial published late last week in the Journal of the American College of Cardiology ( JACC )

demonstrated that HR-HPV18 E2 amplifies the production of ROS and causes a diminish in cellular glutathione (GSH) levels

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The REWIND trial with dulaglutide included many patients without established ASCVD and demonstrated a consistent reduction in MACE, supporting a role in primary prevention, although the effect size was modest