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New England Journal of Medicine, 385(6).
Vollmer K, Holst JJ, Baller B, Ellrichmann M, Nauck MA, Schmidt WE, Meier JJ
Further research is needed to investigate the potential use of semaglutide in the treatment of thyroid cancer
Data from the Phase 2 programme (NEJM, 2023) provide an initial picture of its tolerability, which broadly mirrors that of other incretin-based therapies, with some additional considerations related to its glucagon receptor activity
Semaglutide works best when integrated into a comprehensive weight management plan that includes lifestyle modifications such as dietary improvements, increased physical activity, and behavior-change strategies
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