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A "natural" origin of a substance tells you nothing about overall safety at a synthetic dose, by an unphysiological route, in a manufactured form whose purity is not independently verified
DAlessandro, A
The 2025 narrative review noted that despite the volume of preclinical work, well-controlled human trial data are scarce, and the regenerative findings should be interpreted accordingly (PMID 40789979)
BPC-157 is not FDA-approved for human therapeutic use
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