reasons not to take semaglutide Who should semaglutide? Why Am I Not Losing

Consider contacting your prescriber if: diarrhea persists beyond 4 weeks at a stable dose, you are losing more than 3% of body weight per week, you cannot maintain adequate nutrition or hydration, or OTC management fails to provide relief

By understanding the distinct features, efficacy, and accessibility of these treatments, individuals can make an informed decision that aligns with their weight loss goals and overall well-being

BNF / NICE

A 0.5mg dose requires 30 units instead of 20

SLC7A11 inhibition results in GSH depletion, which downregulates GPX4 levels, thereby promoting cellular/subcellular membrane damage caused by LPOs [28]