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Anything more significant is rare
For context, the fat-mass reductions reported in Billon 2024 roughly 25-30% in diet-induced obese mice over 28 days without exercise are large for a preclinical metabolic agent and explain why the "exercise mimetic" label stuck
Those who stopped regained 14% of their body weight
The dosing guide emphasizes the importance of consistent, long-term adherence for nerve-related applications
That is not a marketing claim
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