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In vivo GTT GTT experiments were performed in homozygous human FcRn Tg32 mice

Acknowledgements We thank Jean-Philippe Leduc-Gaudet, Claire Bnard, Lise Rivollet, and Malika Nadour for constructive comments on the manuscript

While the dramatically higher weight loss results for retatrutide may help some people with severe obesity become healthier, such rapid weight loss might also be cause for concern, says Areesha Moiz, an obesity researcher at Lady Davis Institute and McGill University in Montreal

Ozempic is a GLP-1 receptor agonist that increases insulin secretion, decreases glucagon production, and slows down digestion, collectively working to lower blood sugar levels

This is crucial for maintaining metabolic rate since muscle tissue burns more calories than fat tissue, thereby supporting long-term weight management