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reported an observational comparative study that compared nerve excitability in patients with type 2 DM who received exenatide (n=32), a dipeptidyl peptidase-4 (DPP-4) inhibitor (n=31), or a sodium-glucose cotransporter-2 (SGLT-2) inhibitor (n=27) ( In a retrospective cohort study, Lin et al

Survodutide has also received FDA fast-track designation for adults with MASH (NCT04771273)

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This is worth discussing with your provider to rule out other causes

Tirzepatide is administered as a once-weekly subcutaneous injection, with dosing typically initiated at 2.5 mg (primarily for tolerability) and gradually titrated upward every 4 weeks based on glycemic response and tolerability